Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591147 | 0.86 | KDM4E (0.40) | KDM4ELMNAEPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30648987 | 0.86 | ALDH1A1 (0.42) | KDM4ELMNAEPHX2CYP2D6ALDH1A1 | |
| SCHEMBL2562258 | 0.85 | KDM4E (0.41) | KDM4EEPHX2CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL7720634 | 0.83 | LTA4H (0.36) | LMNASMN1; SMN2EGLN1MEN1KMT2A | |
| SCHEMBL2125093 | 0.82 | ALDH1A1 (0.41) | KDM4ELMNAALDH1A1SMN1; SMN2EGLN1 | |
| SCHEMBL20535410 | 0.82 | ALDH1A1 (0.41) | KDM4ELMNAALDH1A1SMN1; SMN2EGLN1 | |
| SCHEMBL2721141 | 0.81 | TSHR (0.43) | KDM4EALDH1A1SMN1; SMN2EGLN1MEN1 | |
| SCHEMBL34475154 | 0.80 | AKR1B1 (0.45) | KDM4EEPHX2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17022393 | 0.79 | MEN1 (0.46) | KDM4EEPHX2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7716541 | 0.79 | TSHR (0.47) | LMNAHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673958-B2 | Fullerene derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-18 | — | — | US | disclosed |
| US-8440109-B2 | Fullerene derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20120216867-A1 | FULLERENE DERIVATIVES | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120119198-A1 | FULLERENE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120091449-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20110193073-A1 | FULLERENE DERIVATIVE, COMPOSITION AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-11 | — | — | US | disclosed |
| US-20110193072-A1 | FULLERENE DERIVATIVE, COMPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-11 | — | — | US | disclosed |
| US-20110001093-A1 | FULLERENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110193073-A1 | FULLERENE DERIVATIVE, COMPOSITION AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT | CCNE2, CTNNA1, CCNA1 | KDM4E 2687/4885LMNA 1241/4885EPHX2 2295/4885 |
| US-20120119198-A1 | FULLERENE DERIVATIVES | KCNN2, KCNN1, NCS1 | KDM4E 1730/4885LMNA 2952/4885EPHX2 3455/4885 |
| US-20110193072-A1 | FULLERENE DERIVATIVE, COMPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT | C1S, CYP2S1, CCNE2 | KDM4E 1176/4885LMNA 1045/4885EPHX2 1955/4885 |
| US-20110001093-A1 | FULLERENE DERIVATIVE | CCNE2, H1-0, CRY2 | KDM4E 1670/4885LMNA 1412/4885EPHX2 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.