Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 6/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.43 |
| ▸ | HTR1B | P28222 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26078529 | 0.87 | NISCH (0.51) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078454 | 0.83 | HTR1B (0.49) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078506 | 0.82 | ADRA2A (0.46) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078499 | 0.80 | ADRA2C (0.46) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078385 | 0.80 | TAAR1 (0.49) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078581 | 0.80 | TAAR1 (0.46) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078594 | 0.78 | HTR1D (0.48) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078611 | 0.78 | HTR1D (0.48) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078386 | 0.77 | TAAR1 (0.46) | ADRA2CADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL26078494 | 0.77 | ADRA2C (0.48) | ADRA2CADRA1AADRA2AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | ADRA1A, ADRB1, ADRA1D | ADRA2C 8/4885ADRA1A 1/4885ADRA2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.