SCHEMBL26083604

SCHEMBL26083604

Cc1ccn(C(C)(C)N)n1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.41
TDO2 P48775 1/20 0.38
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
USP2 O75604 1/20 0.36
ALOX15 P16050 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24737152 0.77 NOS1 (0.41) NOS1TDO2MAPTRAB9ANPC1
SCHEMBL24813878 0.77 MAPT (0.36) NOS1TDO2MAPTRAB9ANPC1
SCHEMBL19176596 0.76
SCHEMBL6904862 0.74 MAPT (0.38) NOS1TDO2MAPTRAB9ANPC1
SCHEMBL21166137 0.74 MAPT (0.34) NOS1MAPTRAB9ANPC1ATM
SCHEMBL21581037 0.72 ALDH1A1 (0.33) NOS1MAPTRAB9ANPC1ATM
SCHEMBL12436779 0.72 LMNA (0.40) NOS1MAPTRAB9ANPC1ATM
SCHEMBL21732638 0.70 RIPK2 (0.35) NOS1MAPTRAB9ANPC1ATM
SCHEMBL24884220 0.70 NOS1 (0.35) NOS1MAPTRAB9ANPC1ATM
SCHEMBL21241776 0.69 GAA (0.40) NOS1MAPTRAB9ASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11782062-B2 Kits for analysis using nucleic acid encoding and/or label Encodia, Inc. (US) 2023-10-10 US disclosed