Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 10/20 | 0.36 |
| ▸ | GABRD | O14764 | 10/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.36 |
| ▸ | GABRE | P78334 | 10/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837238 | 1.00 | GABRP (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23689989 | 0.77 | MAT2A (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31204111 | 0.73 | TNKS (0.37) | PKMPKLRMEN1KMT2ADDR1 | |
| SCHEMBL25276159 | 0.73 | TNKS (0.37) | PKMPKLRMEN1KMT2ADDR1 | |
| SCHEMBL25232301 | 0.71 | DDR1 (0.36) | PKMPKLRMEN1KMT2ADDR1 | |
| SCHEMBL25229534 | 0.71 | IKBKE (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31172135 | 0.71 | DDR1 (0.36) | PKMPKLRMEN1KMT2ADDR1 | |
| SCHEMBL31172192 | 0.71 | IKBKE (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8890432 | 0.70 | GABRA2 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31172148 | 0.70 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| CN-115023420-A | Pesticidally active fused bicyclic heteroaromatic compounds | 先正达农作物保护股份公司 | 2022-09-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | GABRP 390/4885GABRD 324/4885GABRA1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.