Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 17/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 17/20 | 0.43 |
| ▸ | GABRP | O00591 | 16/20 | 0.43 |
| ▸ | GABRD | O14764 | 16/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 16/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 16/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 16/20 | 0.43 |
| ▸ | GABRE | P78334 | 16/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 16/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 16/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 16/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 16/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837238 | 0.70 | GABRP (0.36) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL26088331 | 0.70 | GABRP (0.36) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8830715 | 0.69 | CYP3A4 (0.50) | CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL9723057 | 0.69 | ALDH1A1 (0.53) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10679118 | 0.68 | GABRA2 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10678078 | 0.68 | GABRA2 (0.40) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10679158 | 0.68 | GABRA2 (0.38) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8830700 | 0.68 | ALDH1A1 (0.51) | CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL5867300 | 0.68 | TLR8 (0.43) | CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL7801737 | 0.68 | GABRB3 (0.48) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010220-A1 | URACIL DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-20 | — | — | WO | disclosed |