SCHEMBL261099

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL261338	0.82	ALDH1A1 (0.44)	APEX1FBP1ADORA3DNA2CASP6
	SCHEMBL4314490	0.78	GRIK1 (0.44)	APEX1GRIK1GRIA1GRIA2GRIA3
	SCHEMBL4628780	0.77	APEX1 (0.47)	APEX1GLAKDM4E
	SCHEMBL260928	0.75	APEX1 (0.57)	APEX1GRIK1GRIA1GRIA2GRIA3
	SCHEMBL260929	0.75	APEX1 (0.57)	APEX1GRIK1GRIA1GRIA2GRIA3
	SCHEMBL4660564	0.72	APEX1 (0.45)	APEX1GLAKDM4E
	SCHEMBL261055	0.71	FBP1 (0.41)	APEX1FBP1ADORA3DNA2CASP6
	SCHEMBL261054	0.71	FBP1 (0.41)	APEX1FBP1ADORA3DNA2CASP6
	SCHEMBL3518684	0.71	GRIK1 (0.46)	APEX1GRIK1GRIA1GRIA2GRIA3
	SCHEMBL2979855	0.70	CCR2 (0.52)	GLAKDM4ECCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.