SCHEMBL26121817

SCHEMBL26121817

CC[C@]1(COC(=O)c2ccc(C)cc2)OC(OC(C)=O)C[C@@H]1OC(=O)c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PRKCG P05129 1/20 0.37
▸ PRKCB P05771 1/20 0.37
▸ PRKCA P17252 1/20 0.37
▸ PRKCE Q02156 1/20 0.37
▸ PRKCD Q05655 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ SCN1A P35498 1/20 0.36
▸ SCN2A Q99250 1/20 0.36
▸ SCN3A Q9NY46 1/20 0.36
▸ RAB9A P51151 4/20 0.36
▸ GAA P10253 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ NPC1 O15118 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ ABCB1 P08183 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26121824 1.00 PRKCG (0.37) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL23409157 0.86 HPGD (0.39) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL26129664 0.82 PRKCA (0.37) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL26135802 0.82 PRKCA (0.37) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL18670633 0.82 PRKCA (0.37) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL18670631 0.82 PRKCA (0.37) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL26123656 0.77 PRKCG (0.40) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL26123217 0.77 PRKCG (0.40) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL29678404 0.74 PRKCA (0.36) PRKCGPRKCBPRKCAPRKCEPRKCD
SCHEMBL18688498 0.73 HPGD (0.44) PRKCGPRKCBPRKCAPRKCEPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035403-A1 NUCLEOSIDE LINE-1 INHIBITORS TRANSPOSON THERAPEUTICS, INC. (US) 2026-02-05 — — US disclosed
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS INC (US) 2025-07-03 — — US disclosed
EP-4499106-A2 NUCLEOSIDE LINE-1 INHIBITORS Transposon Therapeutics, Inc. (US) 2025-02-05 — — EP disclosed
WO-2023192491-A2 NUCLEOSIDE LINE-1 INHIBITORS TRANSPOSON THERAPEUTICS, INC. (US) 2023-10-05 — — WO disclosed
WO-2023192499-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS, INC. (US) 2023-10-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035403-A1 NUCLEOSIDE LINE-1 INHIBITORS L3MBTL1, TDP1, TRDMT1 PRKCG 4745/4885PRKCB 4609/4885PRKCA 4741/4885
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER UNG, OGG1, NTPCR PRKCG 2090/4885PRKCB 2176/4885PRKCA 2192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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