SCHEMBL26124993

SCHEMBL26124993

Nc1ccc(OC(Cc2ccccn2)Cc2ccccn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
HRH1 P35367 1/20 0.44
MEN1 O00255 1/20 0.43
APAF1 O14727 1/20 0.43
KMT2A Q03164 1/20 0.43
PRMT1 Q99873 1/20 0.42
SYK P43405 1/20 0.42
FDPS P14324 1/20 0.41
PTPRA P18433 1/20 0.41
PARP10 Q53GL7 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361386 0.76 PARP10 (0.64) L3MBTL1MAOAMAOBHRH1MEN1
SCHEMBL3571325 0.76 PARP10 (0.64) L3MBTL1MAOAMAOBHRH1MEN1
Water SCHEMBL9719872 0.75 PARP10 (0.62) L3MBTL1MAOAMAOBHRH1MEN1
Hydrochloric Acid SCHEMBL6754354 0.75 PARP10 (0.62) L3MBTL1MAOAMAOBHRH1MEN1
Hydrochloric Acid SCHEMBL124667 0.75 PARP10 (0.62) L3MBTL1MAOAMAOBHRH1MEN1
SCHEMBL7001784 0.74 MAOA (0.53) L3MBTL1MAOAMAOBSMN1; SMN2RAB9A
SCHEMBL3021299 0.73 RAB9A (0.59) L3MBTL1MAOAMAOBHRH1MEN1
SCHEMBL22874558 0.72 POLB (0.53) L3MBTL1MAOAMAOBMEN1APAF1
SCHEMBL26126632 0.71 L3MBTL1 (0.50) L3MBTL1MAOAMAOBGRIN2DGRIN3B
SCHEMBL19779346 0.69 GRIN2D (0.66) L3MBTL1MAOAMAOBGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206762-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-06-26 US disclosed
WO-2023192348-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206762-A1 CONFORMATIONALLY GATED OPTOELECTRONIC MOLECULAR RECTIFIERS OPRM1, TRPA1, ICMT L3MBTL1 1224/4885MAOA 409/4885MAOB 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.