Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 5/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139804 | 0.86 | GABRA1 (0.34) | GABRA1GABRB2IKBKBRXRBRXRA | |
| SCHEMBL14948629 | 0.82 | ALOX15 (0.54) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL7724748 | 0.80 | CES2 (0.45) | RXRBRXRARXRGSMN1; SMN2KMT2A | |
| SCHEMBL27420025 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL16978930 | 0.80 | LMNA (0.48) | GABRA1GABRB2IKBKBRXRBRXRA | |
| SCHEMBL20412762 | 0.78 | SYK (0.36) | IKBKBRXRBRXRAKDM4EALDH1A1 | |
| SCHEMBL18298077 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6170594 | 0.75 | ALDH1A1 (0.47) | GABRA1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL24027300 | 0.73 | CA5A (0.50) | SMN1; SMN2KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL5033914 | 0.73 | CA5A (0.50) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183813-A2 | BORON-CAPPED CLATHROCHELATE AND MACROCYCLIC LIGANDS AND METAL COMPLEXES THEREOF | U-REIF INVESTMENTS LIMITED PARTNERSHIP (CA) | 2023-09-28 | — | — | WO | disclosed |