Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ADH5 | P11766 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716133 | 0.72 | ALDH1A1 (0.49) | DAOMAPTALDH1A1 | |
| SCHEMBL30580646 | 0.71 | LTA4H (0.47) | CYP19A1 | |
| SCHEMBL9807751 | 0.71 | CYP19A1 (0.46) | MAPTFAAHMGLLADH5CYP19A1 | |
| SCHEMBL7527268 | 0.70 | MAPT (0.41) | MAPTFAAHMGLLCYP19A1ALDH1A1 | |
| SCHEMBL31388142 | 0.70 | NAMPT (0.54) | NAMPTTBXAS1 | |
| SCHEMBL31664989 | 0.69 | ALDH1A1 (0.50) | FAAHMGLLALDH1A1 | |
| SCHEMBL30366356 | 0.68 | FAAH (0.44) | MAPTFAAHMGLLCYP19A1TBXAS1 | |
| SCHEMBL1424751 | 0.67 | CYP19A1 (0.47) | MAPTFAAHMGLLCYP19A1TBXAS1 | |
| SCHEMBL13028408 | 0.67 | ADH5 (0.51) | MAPTADH5CYP19A1ALDH1A1 | |
| SCHEMBL354602 | 0.67 | FFAR2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183470-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023183470-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | WO | disclosed |