Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | ATP4A | P20648 | 1/20 | 0.48 |
| ▸ | ATP4B | P51164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193003 | 0.70 | ALDH1A1 (0.44) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL30953833 | 0.69 | ADORA1 (0.97) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL1745165 | 0.69 | ADORA1 (0.97) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL10076399 | 0.69 | ADORA1 (0.64) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL31677643 | 0.69 | SNCA (0.50) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL26136695 | 0.69 | SNCA (0.50) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL26125672 | 0.69 | ALOX5 (0.50) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL29427505 | 0.69 | GLA (1.00) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL5941029 | 0.69 | GLA (1.00) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| Iodide SCHEMBL4957487 | 0.68 | ADORA1 (1.00) | KMT2AMEN1LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | claimed |
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | disclosed |
| WO-2023192595-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | Arkansas State University - Jonesboro (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | TST, GOT2, TPMT | KMT2A 3923/4885MEN1 1975/4885LMNA 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.