Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | PKLR | P30613 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.62 |
| ▸ | IL1RN | P18510 | 1/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | BRD1 | O95696 | 1/20 | 0.60 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.60 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.60 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175506 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAPKMPGRPKLR | |
| SCHEMBL27500195 | 0.86 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL28396503 | 0.85 | PGR (0.77) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL29549847 | 0.85 | PGR (0.77) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL20021987 | 0.85 | PGR (0.77) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL14629169 | 0.83 | LMNA (0.71) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL9479593 | 0.83 | PGR (0.73) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL3242583 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAAKR1C3PKMPGR | |
| SCHEMBL28316252 | 0.82 | LMNA (0.69) | SMN1; SMN2LMNAPKMPGRPKLR | |
| SCHEMBL10356533 | 0.82 | LMNA (0.69) | SMN1; SMN2LMNAAKR1C3PKMPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542556-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1995-07-19 | — | — | EP | claimed |
| CN-108976178-B | Preparation method of chiral sulfonamide organic compound | 云南民族大学 | 2020-06-05 | — | — | CN | disclosed |
| US-20120095044-A1 | TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE INHIBITORS AND USES THEREOF FOR TREATING VASCULAR CALCIFICATION | Sanford-Burnham Medical Research Institute California | 2012-04-19 | — | — | US | disclosed |
| US-8119693-B2 | Tissue non-specific alkaline phosphatase inhibitors and uses thereof for treating vascular calcification | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090156560-A1 | TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE INHIBITORS AND USES THEREOF FOR TREATING VASCULAR CALCIFICATION | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095044-A1 | TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE INHIBITORS AND USES THEREOF FOR TREATING VASCULAR CALCIFICATION | ALPL, CNDP2, ALPI | SMN1; SMN2 4792/4885LMNA 2775/4885AKR1C3 3202/4885 |
| US-20090156560-A1 | TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE INHIBITORS AND USES THEREOF FOR TREATING VASCULAR CALCIFICATION | ALPL, CNDP2, ALPI | SMN1; SMN2 4792/4885LMNA 2775/4885AKR1C3 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.