SCHEMBL14629169

SCHEMBL14629169

O=S(=O)(Nc1ccc2cnncc2c1)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
ALDH1A1 P00352 3/20 0.61
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
PKM P14618 2/20 0.56
KEAP1 Q14145 2/20 0.55
BRD4 O60885 1/20 0.55
BRD1 O95696 1/20 0.55
BRPF1 P55201 1/20 0.55
BRD9 Q9H8M2 1/20 0.55
BRPF3 Q9ULD4 1/20 0.55
IL1RN P18510 1/20 0.55
ERAP1 Q9NZ08 1/20 0.55
GAA P10253 1/20 0.53
GFER P55789 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
AKR1C3 P42330 1/20 0.52
HTR6 P50406 1/20 0.51
FFAR4 Q5NUL3 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10356533 0.83 LMNA (0.69) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL2614387 0.83 SMN1; SMN2 (1.00) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL810795 0.76 KMT2A (0.91) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL14493605 0.76 BRPF1 (0.51) LMNASMN1; SMN2ALDH1A1KEAP1BRPF1
SCHEMBL1460717 0.76 ALDH1A1 (0.80) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL6984638 0.76 SMN1; SMN2 (0.63) LMNASMN1; SMN2ALDH1A1PKMBRD4
SCHEMBL9001184 0.75 KEAP1 (0.79) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL16177855 0.75 KEAP1 (0.60) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL6986051 0.74 LMNA (0.65) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL6985862 0.74 ALDH1A1 (0.78) LMNASMN1; SMN2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed