Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.62 |
| ▸ | BRD1 | O95696 | 4/20 | 0.62 |
| ▸ | BRPF3 | Q9ULD4 | 4/20 | 0.62 |
| ▸ | BRD4 | O60885 | 2/20 | 0.62 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | ATIC | P31939 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PKLR | P30613 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.57 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12230253 | 0.94 | ATM (0.67) | LMNASMN1; SMN2BRPF1BRD1BRPF3 | |
| SCHEMBL7572129 | 0.83 | GLO1 (0.60) | BRPF1BRD1BRPF3BRD9CYP19A1 | |
| SCHEMBL852159 | 0.83 | PRSS1 (0.65) | LMNASMN1; SMN2BRPF1BRD1BRPF3 | |
| SCHEMBL2614387 | 0.82 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2BRPF1BRD1BRPF3 | |
| SCHEMBL7572258 | 0.81 | CYP19A1 (0.75) | CYP19A1PKMARPGRMEN1 | |
| SCHEMBL14645822 | 0.81 | CYP19A1 (0.75) | CYP19A1ATICPKMKDM4EAR | |
| SCHEMBL27500195 | 0.80 | SMN1; SMN2 (0.76) | LMNASMN1; SMN2BRD4PKMPKLR | |
| SCHEMBL9175506 | 0.80 | SMN1; SMN2 (0.76) | LMNASMN1; SMN2CYP19A1PKMPKLR | |
| SCHEMBL1318489 | 0.77 | BRPF1 (0.50) | LMNASMN1; SMN2BRPF1BRD1BRPF3 | |
| SCHEMBL17560673 | 0.77 | BRPF1 (1.00) | BRPF1BRD1BRPF3BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110063951-A | Improve the Compounds and methods for of impaired endogenous fibrinolysis using histone deacetylase mortifier | 赛伦诺科学有限公司 | 2019-07-30 | — | — | CN | disclosed |