Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626883 | 0.74 | RAB9A (0.62) | MAPT | |
| SCHEMBL3671369 | 0.74 | ALDH1A1 (0.62) | MAPT | |
| SCHEMBL9560121 | 0.74 | DYRK1A (0.50) | MAPTKDM5B | |
| SCHEMBL25416696 | 0.74 | CHEK1 (0.42) | MKNK1MAPTKDM5BMAPK1FGFR3 | |
| SCHEMBL26146291 | 0.72 | MET (0.53) | MAPTMAPK1METNQO2PIM1 | |
| SCHEMBL25763254 | 0.71 | ADRA2A (0.37) | MAPK1FGFR3KDRCCNCCDK8 | |
| SCHEMBL16700180 | 0.71 | MKNK1 (0.53) | MKNK1MAPTMAPK1FGFR3KDR | |
| SCHEMBL2904195 | 0.71 | ALDH1A1 (0.46) | MAPT | |
| SCHEMBL23974987 | 0.71 | PIM1 (0.47) | MAPTKDM5BMAPK1METNQO2 | |
| SCHEMBL23162341 | 0.71 | FLT3 (0.50) | METNQO2CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081923-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Frequency Therapeutics, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |