Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157119 | 0.80 | SIGMAR1 (0.48) | SIGMAR1PARP1HTR6ALDH1A1TSHR | |
| SCHEMBL26157116 | 0.75 | DRD2 (0.42) | LMNATP53MAPTSIGMAR1ALDH1A1 | |
| SCHEMBL26157092 | 0.73 | ALDH1A1 (0.37) | LMNATP53MAPTALDH1A1TSHR | |
| SCHEMBL14601668 | 0.71 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL8575395 | 0.69 | SIGMAR1 (0.62) | SIGMAR1PARP1DRD2 | |
| SCHEMBL11938943 | 0.69 | SIGMAR1 (0.65) | SIGMAR1HTR6DRD2 | |
| SCHEMBL26157227 | 0.68 | ALDH1A1 (0.33) | MAPTALDH1A1TSHRL3MBTL1GPR119 | |
| SCHEMBL256663 | 0.67 | SIGMAR1 (0.63) | SIGMAR1PARP1 | |
| SCHEMBL12523970 | 0.67 | GPR119 (0.50) | LMNATP53MAPTALDH1A1TSHR | |
| SCHEMBL26157121 | 0.67 | DRD2 (0.51) | LMNAMAPTSIGMAR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |