⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiouracil SCHEMBL18815516 | 0.85 | TP53 (0.76) | — | |
| Pyrrolidine SCHEMBL2452735 | 0.85 | MMP2 (0.72) | — | |
| Uracil SCHEMBL5089507 | 0.74 | — | — | |
| Uracil SCHEMBL8235 | 0.74 | — | — | |
| Uracil SCHEMBL3798527 | 0.74 | CRBN (1.00) | — | |
| Uracil SCHEMBL11607890 | 0.74 | — | — | |
| Uracil SCHEMBL28120281 | 0.74 | TP53 (0.83) | — | |
| Uracil SCHEMBL16116311 | 0.72 | — | — | |
| Uracil SCHEMBL710130 | 0.72 | — | — | |
| Uracil SCHEMBL8767625 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 45754 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630827-B2 | Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies | ROGCON, INC. (US) | 2026-05-19 | — | — | US | claimed |
| CN-122029177-A | Oligonucleotides containing multiple ligands and/or lipids | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122028913-A | Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122029176-A | Containing a plurality of oligonucleotides modified oligonucleotides | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260109977-A1 | MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION | TRILINK BIOTECHNOLOGIES, LLC (US) | 2026-04-23 | — | — | US | claimed |
| US-20260103824-A1 | Compositions and Methods for Selectively Synthesizing Triple-indexed cDNA Libraries | UNIV ROCKEFELLER (US) | 2026-04-16 | — | — | US | claimed |
| US-12577554-B2 | Methods for purification of messenger RNA | TRANSLATE BIO, INC. (US) | 2026-03-17 | — | — | US | claimed |
| US-12569572-B2 | Messenger RNA therapy for the treatment of Friedreich's ataxia | TRANSLATE BIO, INC. (US) | 2026-03-10 | — | — | US | claimed |
| US-12552858-B2 | Methods and compositions for delivering mRNA coded antibodies | TRANSLATE BIO, INC. (US) | 2026-02-17 | — | — | US | claimed |
| EP-4676446-A1 | NOVEL LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | CureVac SE (DE) | 2026-01-14 | — | — | EP | claimed |
| EP-0618925-A1 | GAPPED 2' MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-12 | — | — | EP | claimed |
| WO-1993013121-A1 | GAPPED 2' MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | claimed |
| EP-0506935-A1 | NOVEL RIBONUCLEOSIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND DRUGS CONTAINING SAID COMPOUNDS | PASTEUR MERIEUX SERUMS ET VACCINS, Société Anonyme : (FR) | 1992-10-07 | — | — | EP | claimed |
| EP-0406309-A4 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | — | 1992-08-19 | — | — | EP | claimed |
| US-5126439-A | Complementary purines and pyrimidines | TEMPLE UNIVERSITY (US) | 1992-06-30 | — | — | US | claimed |
| WO-1992006993-A1 | NOVEL RIBONUCLEOSIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND DRUGS CONTAINING SAID COMPOUNDS | PASTEUR MERIEUX SERUMS ET VACCINS (FR) | 1992-04-30 | — | — | WO | claimed |
| EP-0406309-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1991-01-09 | — | — | EP | claimed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | claimed |
| US-4604167-A | Silver plating solution and silver plating process and pretreatment solution therefor | SHINKO ELECTRIC INDUSTRIES CO., LTD. (JP) | 1986-08-05 | — | — | US | claimed |
| US-4010075-A | FERMENTATION OF STREPTOMYCES | THE UPJOHN COMPANY (US) | 1977-03-01 | — | — | US | claimed |