Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745118 | 1.00 | RAB9A (0.50) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL8924537 | 1.00 | RAB9A (0.50) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL11332706 | 0.83 | MAPT (0.52) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL11327606 | 0.83 | MAPT (0.52) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL745116 | 0.77 | RAB9A (0.49) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL745117 | 0.77 | RAB9A (0.49) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL21838458 | 0.77 | RAB9A (0.49) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL21838460 | 0.77 | RAB9A (0.49) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL30220799 | 0.77 | RAB9A (0.49) | RAB9ATDP1MAPTHTTGAA | |
| SCHEMBL15992321 | 0.74 | KMT2A (0.37) | RAB9ATDP1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856230-B2 | Enzyme inhibitors | UNIVERSITY OF SUNDERLAND (GB) | 2018-01-02 | — | — | US | disclosed |
| US-20170246130-A1 | 4-HYDROXYBENZOHYDARZIDE-A NEW CLASS OF ANGIOGENIC ENZYME THYMIDINE PHOSPHORYLASE INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2017-08-31 | — | — | US | disclosed |
| US-9675734-B2 | Medical balloon coated with therapeutic agent, carboxylic acid, and salt thereof | INVATEC S.P.A. (IT) | 2017-06-13 | — | — | US | disclosed |
| US-9675734-B2 | Medical balloon coated with therapeutic agent, carboxylic acid, and salt thereof | INVATEC S.P.A. (IT) | 2017-06-13 | — | — | US | disclosed |
| US-20160058915-A1 | Medical Balloon Coated With Therapeutic Agent, Carboxylic Acid, and Salt Thereof | INVATEC S.P.A. (IT) | 2016-03-03 | — | — | US | disclosed |
| US-20160058915-A1 | Medical Balloon Coated With Therapeutic Agent, Carboxylic Acid, and Salt Thereof | INVATEC S.P.A. (IT) | 2016-03-03 | — | — | US | disclosed |
| US-20150322035-A1 | Enzyme Inhibitors | UNIVERSITY OF SUNDERLAND (GB) | 2015-11-12 | — | — | US | disclosed |
| US-20150322035-A1 | Enzyme Inhibitors | UNIVERSITY OF SUNDERLAND (GB) | 2015-11-12 | — | — | US | disclosed |
| US-20130230592-A1 | NOVEL OMEGA-3 AND OMEGA-6 FATTY ACID COMPOSITIONS AND USES THEREOF | TERREAUX CHRISTIAN (CH) | 2013-09-05 | — | — | US | disclosed |
| US-20130230592-A1 | NOVEL OMEGA-3 AND OMEGA-6 FATTY ACID COMPOSITIONS AND USES THEREOF | TERREAUX CHRISTIAN (CH) | 2013-09-05 | — | — | US | disclosed |
| US-20120101157-A1 | 4,5-Diamino-3-Halo-2-Hydroxybenzoic Acid Derivatives and Preparations Thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-04-26 | — | — | US | disclosed |
| US-20120101157-A1 | 4,5-Diamino-3-Halo-2-Hydroxybenzoic Acid Derivatives and Preparations Thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-04-26 | — | — | US | disclosed |
| EP-1925942-A1 | Method for diagnosing diabetes mellitus | Schiffer, Roswitha (DE) | 2008-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322035-A1 | Enzyme Inhibitors | TXNRD3, TXNRD2, TXNRD1 | RAB9A 4548/4885TDP1 323/4885MAPT 2655/4885 |
| US-20130230592-A1 | NOVEL OMEGA-3 AND OMEGA-6 FATTY ACID COMPOSITIONS AND USES THEREOF | ALOX5, ELOVL6, VDR | RAB9A 1995/4885TDP1 3214/4885MAPT 1002/4885 |
| US-20120101157-A1 | 4,5-Diamino-3-Halo-2-Hydroxybenzoic Acid Derivatives and Preparations Thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH3, HRH2 | RAB9A 768/4885TDP1 3831/4885MAPT 4509/4885 |
| US-20170246130-A1 | 4-HYDROXYBENZOHYDARZIDE-A NEW CLASS OF ANGIOGENIC ENZYME THYMIDINE PHOSPHORYLASE INHIBITORS | TYMP, DPYD, FLT4 | RAB9A 4698/4885TDP1 120/4885MAPT 4301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.