Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of 2-Ethylhexanoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylhexanoic Acid SCHEMBL28837492 | 1.00 | CA2 (0.91) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL8927360 | 0.98 | CA2 (0.88) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL1434321 | 0.98 | CA2 (0.88) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL15094118 | 0.98 | CA2 (0.88) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL11117619 | 0.98 | CA2 (0.88) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL2119249 | 0.98 | CA2 (0.96) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL1110958 | 0.98 | CA2 (0.88) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL10809985 | 0.96 | CA2 (0.84) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL23802667 | 0.95 | CA2 (0.91) | CA2MAPK1CA1CYP3A4TSHR | |
| 2-Ethylhexanoic Acid SCHEMBL56210 | 0.95 | CA2 (1.00) | CA2MAPK1CA1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9396 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747302-A2 | REPAIR AND OPTIMIZATION OF NANOCOMPOSITE MATERIALS | Nanocore ApS (DK) | 2026-05-27 | — | — | EP | claimed |
| CN-122037136-A | Preparation method of polyisocyanate curing agent | 万华化学集团股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037135-A | Composition, polyurethane foam material, preparation method of polyurethane foam material and refrigeration equipment | TCL家用电器（合肥）有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20260132306-A1 | EXPANDABLE PROTECTIVE COATING | H K WENTWORTH LTD (GB) | 2026-05-14 | — | — | US | claimed |
| EP-4253442-B1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-04-29 | — | — | EP | claimed |
| EP-4717730-A1 | CHEMICAL RECYCLYING OF WASTE FLEXIBLE POLYURETHANE FOAM TO RIGID POLYUERTHANE FOAM MATERIALS | Foam Ecosolution Innovation, Inc. (CA) | 2026-04-01 | — | — | EP | claimed |
| US-20260062514-A1 | METHODS OF PREPARING ULTRA-LOW DENSITY SPRAY POLYURETHANE FOAM AND USES THEREOF | GENERAL COATINGS MFG CORP (US) | 2026-03-05 | — | — | US | claimed |
| US-20260042893-A1 | Chemical Recycling of Waste Flexible Polyurethane Foam to Rigid Polyurethane Foam Materials | Foam Ecosolution Innovation (CA) | 2026-02-12 | — | — | US | claimed |
| US-12540214-B2 | HCFO-containing isocyanate-reactive compositions, related foam-forming compositions and polyurethane foams | COVESTRO LLC (US) | 2026-02-03 | — | — | US | claimed |
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-01-29 | — | — | US | claimed |
| US-4256846-A | POLYETHER POLYOLS, ALKALI METAL CARBOXYLATES, TERTIARY AMINES | BRIDGESTONE TIRE CO., LTD. (JP) | 1981-03-17 | — | — | US | claimed |
| US-4256799-A | A RIGID FOAM CORE OF A URETHANE-MODIFIED POLYISOCYANURATE; CONSTRUCTION MATERIALS; INSULATION; LOW DENSITY; ASBESTOS, FOILS, AND GLASS FIBER LAYERS | BRIDGESTONE TIRE CO., LTD. (JP) | 1981-03-17 | — | — | US | claimed |
| US-4212917-A | FROM POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE AND ETHOXYLATED GLYCEROL, PENTAERYTHRITOL OR TRIMETHYLOL-PROPANE OR -ETHANE | THE CELOTEX CORPORATION (US) | 1980-07-15 | — | — | US | claimed |
| US-4205136-A | REACTING 3-METHYLPENTANE-1,3,5-TRIOL WITH POLYOL AND POLYISOCYANATE | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1980-05-27 | — | — | US | claimed |
| US-4166164-A | ALKALI METAL CARBOXYLATE | BASF WYANDOTTE CORPORATION (US) | 1979-08-28 | — | — | US | claimed |
| EP-0002281-A1 | Process for the preparation of carbodiimide-isocyanurate foams | BASF WYANDOTTE CORPORATION (US) | 1979-06-13 | — | — | EP | claimed |
| US-4142059-A | Spray drying sodium and potassium 2-ethylhexanoate | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | claimed |
| US-4126742-A | High-modulus polyisocyanurate elastomers | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | claimed |
| US-4126741-A | High-modulus polyisocyanurate elastomers | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | claimed |
| US-4101465-A | TO POLYISOCYANURATES, ALKALI METAL GLYCINE SALTS, QUATERNARY AMMONM CARBOXYLATES, ALKALI METAL SALTS OF AMIDES AND ACIDS | THE UPJOHN COMPANY (US) | 1978-07-18 | — | — | US | claimed |