2-Ethylhexanoic Acid

2-Ethylhexanoic Acid

SCHEMBL56210

CCCCC(CC)C(=O)[O-].[Na+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of 2-Ethylhexanoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 9/20 1.00
CA1 known ✓ P00915 7/20 0.59
MAPK1 P28482 1/20 0.61
NFKB1 P19838 3/20 0.60
CYP3A4 P08684 2/20 0.60
TSHR P16473 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
GPR84 Q9NQS5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethylhexanoic Acid SCHEMBL9147740 1.00 CA2 (1.00) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL9413782 0.98 CA2 (0.96) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL3649881 0.98 CA2 (0.96) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL2119249 0.98 CA2 (0.96) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL23802667 0.95 CA2 (0.91) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL6313729 0.95 CA2 (0.91) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL2400572 0.95 CA2 (0.91) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL20582677 0.95 CA2 (0.91) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL21569275 0.95 CA2 (0.91) CA2MAPK1NFKB1CYP3A4TSHR
2-Ethylhexanoic Acid SCHEMBL170609 0.95 CA2 (0.91) CA2MAPK1NFKB1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6951 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2964381-B2 CATALYST FOR THE CROSS-LINKING OF SILICON RUBBERS NITROCHEMIE GMBH (DE) 2026-05-27 EP claimed
CN-122080447-A Coated particles and method of making same 2026-05-26 CN claimed
CN-118791807-B Rapidly cured rigid crosslinked polyvinyl chloride foam and preparation method thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
EP-4253442-B1 AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS EVONIK OPERATIONS GMBH (DE) 2026-04-29 EP claimed
US-20260028445-A1 AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS EVONIK OPERATIONS GMBH (DE) 2026-01-29 US claimed
EP-4592292-A1 STABLE MONOHYDRATE FORM OF AVIBACTAM SODIUM SALT AND PREPARATION METHOD THEREFOR Kyongbo Pharm. Co., Ltd. (KR) 2025-07-30 EP claimed
CN-120156168-A Transparent polyester base film with strippable invisible car cover and preparation method thereof 北京车服节能环保科技有限公司 2025-06-17 CN claimed
EP-4565582-A1 PROCESS FOR THE PREPARATION OF ISAVUCONAZONIUM MONOSULFATE Icrom SpA (IT) 2025-06-11 EP claimed
EP-4562069-A1 TERTIARY AMINO-AMIDE COMPOSITION USEFUL IN MAKING POLYURETHANE POLYMERS Evonik Operations GmbH (DE) 2025-06-04 EP claimed
EP-4562070-A1 METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM Evonik Operations GmbH (DE) 2025-06-04 EP claimed
US-4327222-A REACTING AN ARYL SUBSTITUTED KETONE WITH HYDROXYLAMINE TO FORM OXIME, THEN CYCLIZATION WITH BUTYLLITHIUM CDC LIFE SCIENCES INC. (CA) 1982-04-27 US claimed
EP-0039967-A1 Solvate of amoxicillin, process for the preparation thereof and process for the preparation of injectable preparations from this solvate GIST-BROCADES N.V. (NL) 1981-11-18 EP claimed
US-4288513-A Photoresist of polyvinyl alcohol and ferric dichromate GTE LABORATORIES INCORPORATED (US) 1981-09-08 US claimed
US-4277601-A Preparation of sodium cefuroxime GLAXO GROUP LIMITED (GB) 1981-07-07 US claimed
EP-0026928-A1 3,4-Diarylisoxazol-5-acetic acid compounds, process for preparing the same, and pharmaceuticals containing the same CDC Life Sciences Inc. (CA) 1981-04-15 EP claimed
EP-0001024-B1 CRYSTALLINE FORM OF THE SODIUM SALT OF AN OXYIMINO DERIVATIVE OF THE 7-AMINOTHIAZOLYLACETAMIDO-CEPHALOSPORANIC ACID, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT ROUSSEL-UCLAF (FR) 1981-01-21 EP claimed
US-4224371-A SALT FORMATION, HYDRATION ROUSSEL UCLAF (FR) 1980-09-23 US claimed
US-4142059-A Spray drying sodium and potassium 2-ethylhexanoate ELI LILLY AND COMPANY (US) 1979-02-27 US claimed
US-4104470-A Crystallization process for cefazolin sodium ELI LILLY AND COMPANY (US) 1978-08-01 US claimed
US-3957706-A POLYETHERESTERS, SODIUM CARBOXYLATE EASTMAN KODAK COMPANY (US) 1976-05-18 US claimed