Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623746 | 0.86 | — | — | |
| SCHEMBL2632415 | 0.86 | KIF11 (0.49) | RORCKIF11CYP3A4MLYCDCYP3A5 | |
| SCHEMBL2623744 | 0.82 | ALDH1A1 (0.38) | KIF11CYP3A4ALDH1A1 | |
| SCHEMBL2623745 | 0.81 | ABCG2 (0.32) | — | |
| SCHEMBL2623742 | 0.78 | DHFR (0.37) | KIF11CYP3A4ALDH1A1CYP19A1 | |
| SCHEMBL2632431 | 0.76 | KIF11 (0.38) | KIF11CYP3A4ALDH1A1 | |
| SCHEMBL26043033 | 0.72 | DHFR (0.38) | KIF11CYP3A4ALDH1A1 | |
| SCHEMBL2623732 | 0.71 | ALDH1A1 (0.38) | ALDH1A1ELANE | |
| SCHEMBL2632428 | 0.71 | CYP3A4 (0.40) | KIF11CYP3A4ALDH1A1CYP19A1 | |
| SCHEMBL2632320 | 0.71 | TSHR (0.39) | MAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | HSD17B2, CYP1A2, HSD17B1 | RORC 209/4885KIF11 1884/4885CYP3A4 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.