Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623746 | 0.95 | — | — | |
| SCHEMBL2632320 | 0.89 | TSHR (0.39) | ABCG2MEN1NPC1KMT2ATSHR | |
| SCHEMBL2632322 | 0.84 | CYP2A6 (0.34) | TSHR | |
| SCHEMBL13720708 | 0.82 | TSHR (0.43) | ABCG2MEN1NPC1KMT2ATSHR | |
| SCHEMBL2623748 | 0.81 | RORC (0.37) | — | |
| SCHEMBL12533827 | 0.76 | ALDH1A1 (0.42) | MEN1NPC1KMT2ATSHRCRHBP | |
| SCHEMBL10038768 | 0.76 | ALDH1A1 (0.42) | MEN1NPC1KMT2ATSHRCRHBP | |
| SCHEMBL13037674 | 0.76 | CYP2A6 (0.38) | MEN1NPC1KMT2ATSHR | |
| SCHEMBL2623728 | 0.76 | L3MBTL1 (0.37) | MEN1KMT2ATSHRCRHBPCRHR2 | |
| SCHEMBL10038680 | 0.74 | ABCG2 (0.33) | ABCG2MEN1NPC1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AT) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120091884-A1 | HEPTAAZAPHENALENE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | HSD17B2, CYP1A2, HSD17B1 | ABCG2 3102/4885MEN1 3492/4885NPC1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.