SCHEMBL26246771

SCHEMBL26246771

CC(=O)COc1cccc(-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.56
RXRB P28702 1/20 0.56
MRGPRX4 Q96LA9 1/20 0.54
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
ALDH1A1 P00352 2/20 0.52
USP2 O75604 1/20 0.52
HPGD P15428 1/20 0.52
LMNA P02545 2/20 0.51
PTGER4 P35408 1/20 0.51
MAOB P27338 1/20 0.51
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
STAT1 P42224 1/20 0.50
PDCD1 Q15116 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
NR4A2 P43354 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
GGPS1 O95749 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420401 0.86 ALOX15 (0.68) RXRARXRBMRGPRX4LMNANR4A2
SCHEMBL6298211 0.85 LMNA (0.61) NPC1RAB9AALDH1A1HPGDLMNA
SCHEMBL7733929 0.84 MAPT (0.66) NPC1RAB9AALDH1A1USP2HPGD
SCHEMBL7746 0.83 ALOX15 (0.68) NPC1RAB9AHPGDLMNAKMT2A
SCHEMBL9256522 0.82 PRMT6 (0.48) RXRARXRBNPC1RAB9AALDH1A1
SCHEMBL3096634 0.80 MAOB (0.68) MRGPRX4RAB9AALDH1A1MAOBKMT2A
SCHEMBL404889 0.80 KMT2A (0.54) MRGPRX4NPC1RAB9AALDH1A1LMNA
SCHEMBL27997601 0.80 KMT2A (0.54) MRGPRX4NPC1RAB9AALDH1A1LMNA
SCHEMBL12411431 0.79 KMT2A (0.66) MRGPRX4NPC1RAB9ALMNAMAOB
SCHEMBL8264165 0.79 PPARG (0.51) NPC1RAB9ALMNAMAOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255933-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS CRESCENTA BIOSCIENCES (US) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255933-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS FABP1, FABP4, FABP5 RXRA 13/4885RXRB 14/4885MRGPRX4 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.