Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261099 | 0.87 | LMNA (0.53) | ALDH1A1HPGDRXRARXRBLMNA | |
| SCHEMBL9258359 | 0.84 | F9 (0.54) | ALDH1A1HPGDRXRARXRBCHEK2 | |
| SCHEMBL26246771 | 0.82 | RXRA (0.56) | MAOBALDH1A1USP2HPGDRXRA | |
| SCHEMBL30963937 | 0.80 | RXRA (0.51) | PRMT6RXRARXRBCHEK2CYP2E1 | |
| SCHEMBL9255828 | 0.80 | MC4R (0.40) | PRMT6MC4RRXRARXRBCHEK2 | |
| SCHEMBL9255143 | 0.79 | LTB4R (0.39) | PRMT6MC4RRXRARXRBCHEK2 | |
| SCHEMBL9257607 | 0.79 | ALDH1A1 (0.47) | PRMT6ALDH1A1CNR1CYP2E1CYP2A6 | |
| SCHEMBL9260900 | 0.79 | LTB4R (0.45) | RXRARXRBLMNASLC6A9CYP2E1 | |
| SCHEMBL6298211 | 0.78 | LMNA (0.61) | MAOBALDH1A1HPGDLMNANPC1 | |
| SCHEMBL9256741 | 0.77 | LMNA (0.40) | PRMT6RXRARXRBLMNASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |