SCHEMBL2628322

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30646324	0.87	KIF11 (0.46)	ACHEGAAL3MBTL1KDM4EUTS2R
	SCHEMBL2628357	0.87	KIF11 (0.46)	ACHEGAAL3MBTL1KDM4EUTS2R
	SCHEMBL2628367	0.79	ACHE (0.56)	ACHEGAAL3MBTL1UTS2RGABRP
	SCHEMBL30646329	0.78	ACHE (0.54)	ACHEGAAKDM4EALDH1A1NPC1
	SCHEMBL29111450	0.78	ACHE (0.54)	ACHEGAAKDM4EALDH1A1NPC1
	SCHEMBL29111452	0.77	KIF11 (0.51)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL30646322	0.77	KIF11 (0.51)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL2628332	0.76	GABRA1 (0.56)	ACHEKDM4EGABRPGABRDGABRA1
	SCHEMBL17453383	0.76	UTS2R (0.56)	ACHEGAAL3MBTL1KDM4EUTS2R
	SCHEMBL10440555	0.75	PARP1 (0.55)	ACHEKDM4EUTS2RGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.