SCHEMBL26292635

CC[C@H](C)[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CC(C)C)[C@@H](C)O)C(c2ccccc2)c2ccccc2)CSSC(C)(C)[C@@H](C(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)C[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	8/20	0.46

▸	CALCR	P30988	8/20	0.46

▸	SLC40A1	Q9NP59	1/20	0.46

▸	CSNK2A2	P19784	1/20	0.45

▸	CSNK2B	P67870	1/20	0.45

▸	CSNK2A1	P68400	1/20	0.45

▸	CSNK2A3	Q8NEV1	1/20	0.45

▸	HSP90AB1	P08238	1/20	0.45

▸	NPY2R	P49146	5/20	0.44

▸	NR3C1	P04150	1/20	0.44

▸	CTNNB1	P35222	1/20	0.44

▸	PRLHR	P49683	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25944583	0.98	SLC40A1 (0.46)	RAMP3CALCRSLC40A1CSNK2A2CSNK2B
SCHEMBL25944461	0.94	HSP90AB1 (0.47)	CSNK2A2CSNK2BCSNK2A1CSNK2A3HSP90AB1
SCHEMBL26292602	0.94	RAMP3 (0.49)	RAMP3CALCRSLC40A1CSNK2A2CSNK2B
SCHEMBL26292620	0.92	RAMP3 (0.47)	RAMP3CALCRSLC40A1CSNK2A2CSNK2B
SCHEMBL26292629	0.92	RAMP3 (0.47)	RAMP3CALCRSLC40A1CSNK2A2CSNK2B
SCHEMBL26307010	0.91	NPY2R (0.48)	CSNK2A2CSNK2BCSNK2A1CSNK2A3HSP90AB1
SCHEMBL29311618	0.89	CSNK2A2 (0.46)	RAMP3CALCRSLC40A1CSNK2A2CSNK2B
SCHEMBL29311858	0.89	KCNA3 (0.43)	SLC40A1CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL25946013	0.87	SLC40A1 (0.48)	RAMP3CALCRSLC40A1CSNK2A2CSNK2B
SCHEMBL29311844	0.87	APLNR (0.43)	SLC40A1CSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230295259-A1	Conjugated Hepcidin Mimetics	PROTAGONIST THERAPEUTICS, INC.	2023-09-21	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230295259-A1	Conjugated Hepcidin Mimetics	HAMP, VIP, HDGF	RAMP3 821/4885CALCR 148/4885SLC40A1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.