SCHEMBL29311618

SCHEMBL29311618

CC[C@H](C)[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](NC(=O)[C@H](CC(N)/N=N\N)NC(=O)CC(C)C)[C@@H](C)O)C(c2ccccc2)c2ccccc2)CSSC[C@@H](C(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)C[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCN)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CSNK2A2 P19784 1/20 0.46
▸ CSNK2B P67870 1/20 0.46
▸ CSNK2A1 P68400 1/20 0.46
▸ CSNK2A3 Q8NEV1 1/20 0.46
▸ RAMP3 O60896 6/20 0.45
▸ CALCR P30988 6/20 0.45
▸ NPY2R P49146 5/20 0.44
▸ INSR P06213 1/20 0.44
▸ NR3C1 P04150 1/20 0.44
▸ SLC40A1 Q9NP59 1/20 0.44
▸ KCNA3 P22001 1/20 0.43
▸ KCNA1 Q09470 1/20 0.43
▸ CXCR4 P61073 1/20 0.43
▸ GLP1R P43220 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26292602 0.93 RAMP3 (0.49) CSNK2A2CSNK2BCSNK2A1CSNK2A3RAMP3
SCHEMBL26292620 0.91 RAMP3 (0.47) CSNK2A2CSNK2BCSNK2A1CSNK2A3RAMP3
SCHEMBL26292629 0.91 RAMP3 (0.47) CSNK2A2CSNK2BCSNK2A1CSNK2A3RAMP3
SCHEMBL26307010 0.91 NPY2R (0.48) CSNK2A2CSNK2BCSNK2A1CSNK2A3NPY2R
SCHEMBL29311858 0.89 KCNA3 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3NPY2R
SCHEMBL26292635 0.89 RAMP3 (0.46) CSNK2A2CSNK2BCSNK2A1CSNK2A3RAMP3
SCHEMBL29311844 0.88 APLNR (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3NPY2R
SCHEMBL25944583 0.87 SLC40A1 (0.46) CSNK2A2CSNK2BCSNK2A1CSNK2A3RAMP3
SCHEMBL26305035 0.87 NPY2R (0.47) CSNK2A2CSNK2BCSNK2A1CSNK2A3NPY2R
SCHEMBL29311547 0.87 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3NPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226225-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226225-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, SLC40A1, FTH1 CSNK2A2 4835/4885CSNK2B 4852/4885CSNK2A1 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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