Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 19/20 | 0.50 |
| ▸ | NOS1 | P29475 | 16/20 | 0.50 |
| ▸ | NOS3 | P29474 | 15/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26313813 | 0.87 | NOS2 (0.42) | NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL25410821 | 0.86 | NOS2 (0.41) | NOS2NOS1NOS3 | |
| SCHEMBL26313647 | 0.84 | NOS2 (0.52) | NOS2NOS1NOS3PGR | |
| SCHEMBL26313668 | 0.83 | CRHR1 (0.40) | NOS2NOS1NOS3 | |
| SCHEMBL25409199 | 0.80 | NOS2 (0.40) | NOS2NOS1NOS3PGR | |
| SCHEMBL25414063 | 0.79 | ADRA1D (0.39) | NOS2NOS1NOS3PGR | |
| SCHEMBL26313798 | 0.77 | IDO1 (0.43) | NOS2 | |
| SCHEMBL30597303 | 0.77 | IDO1 (0.43) | NOS2 | |
| SCHEMBL30433862 | 0.73 | ALDH3A1 (0.51) | — | |
| SCHEMBL26313650 | 0.73 | GPBAR1 (0.43) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | Gacter Inc. (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | NOS1, NOS3, NOS2 | NOS2 3/4885NOS1 1/4885NOS3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.