Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559919 | 0.79 | LMNA (0.36) | VDRMAPTMEN1KMT2ATHRB | |
| SCHEMBL1655903 | 0.79 | MEN1 (0.55) | VDRMAPTMEN1KMT2ATHRB | |
| SCHEMBL1655907 | 0.79 | MEN1 (0.55) | VDRMAPTMEN1KMT2ATHRB | |
| SCHEMBL9998464 | 0.77 | HTT (0.46) | MAPTMEN1KMT2ATHRBLMNA | |
| SCHEMBL13496725 | 0.77 | HTT (0.46) | MAPTMEN1KMT2ATHRBLMNA | |
| SCHEMBL15185614 | 0.76 | VDR (0.36) | VDRMAPTMEN1KMT2ATHRB | |
| SCHEMBL14781535 | 0.75 | ALDH1A1 (0.33) | VDRLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL14945226 | 0.74 | HTT (0.54) | MAPTMEN1KMT2ATHRBLMNA | |
| SCHEMBL1709062 | 0.74 | HTT (0.50) | MAPTMEN1KMT2ATHRBLMNA | |
| SCHEMBL19662368 | 0.74 | FOLH1 (0.48) | MAPTMEN1KMT2ATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234566-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | BGI Shenzhen (CN) | 2023-08-30 | — | — | EP | disclosed |