Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793051 | 0.85 | RAB9A (0.58) | POLBALDH1A1RAB9AGAANPC1 | |
| SCHEMBL25412714 | 0.85 | HPGDS (0.56) | MAOAACHEPOLBTLR7PANK3 | |
| SCHEMBL29600613 | 0.82 | MAOA (0.57) | MAOAACHEPIM1PIM3 | |
| SCHEMBL25410319 | 0.81 | KDM4E (0.55) | ACHEALDH1A1TLR7GAAHTR2C | |
| SCHEMBL25413056 | 0.81 | RAB9A (0.44) | MAOAACHEPOLBALDH1A1TLR7 | |
| SCHEMBL14656020 | 0.81 | ACHE (0.64) | MAOAACHEPOLBALDH1A1RAB9A | |
| SCHEMBL26469879 | 0.79 | ACHE (0.57) | MAOAACHEPOLBALDH1A1TLR7 | |
| SCHEMBL26319783 | 0.78 | ALDH1A1 (0.55) | ACHEALDH1A1IRAK4 | |
| SCHEMBL29910977 | 0.78 | MAOA (0.61) | MAOAACHEPOLBALDH1A1TLR7 | |
| SCHEMBL25278483 | 0.77 | MAOA (0.58) | MAOAACHETLR7RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170024-A1 | CAMK2 MODULATORS AND THEIR USE IN MEDICINE | UNIVERSITY OF COPENHAGEN (DK) | 2023-09-14 | — | — | WO | disclosed |