Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.47 |
| ▸ | ALPG | P10696 | 3/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196653 | 0.90 | ALPL (0.59) | ALPLALPGGCGRHSD17B1HSD17B2 | |
| SCHEMBL26320533 | 0.78 | MAPT (0.43) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL26320568 | 0.76 | ALPL (0.80) | ALPLALPGGCGRCYP1A2CYP3A4 | |
| SCHEMBL16625012 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL26320537 | 0.74 | ALPL (0.47) | ALPLALPGGCGRHSD17B1HSD17B2 | |
| SCHEMBL3595617 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL30149949 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL7905772 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL26320526 | 0.70 | ALDH1A1 (0.43) | ALPLALPGHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL9636277 | 0.67 | ALDH1A1 (0.65) | CYP1A2CYP2D6ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPL 4374/4885ALPG 4545/4885GCGR 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.