Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26324940 | 0.89 | TRPM8 (0.39) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL26324999 | 0.89 | ALOX5 (0.37) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL25440267 | 0.86 | HSD17B1 (0.42) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL26324800 | 0.81 | TSHR (0.42) | ALDH1A1MAPTHTTKMT2ANPSR1 | |
| SCHEMBL26324980 | 0.80 | PDCD1 (0.39) | HSD17B1HSD17B2MAPTHTTKMT2A | |
| SCHEMBL26324996 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1HTTKMT2A | |
| SCHEMBL26324981 | 0.79 | MEN1 (0.38) | MAPTMEN1KMT2ANPSR1MAPK1 | |
| SCHEMBL26325013 | 0.78 | PDCD1 (0.44) | MAPTRAB9ANPC1 | |
| SCHEMBL26324955 | 0.78 | PDCD1 (0.50) | MAPTRAB9ANPC1 | |
| SCHEMBL26325014 | 0.76 | PDCD1 (0.51) | MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | HSD17B1 4720/4885HSD17B2 4306/4885ALDH1A1 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.