Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26324999 | 0.94 | ALOX5 (0.37) | ALDH1A1NPSR1TDP1TSHRKMT2A | |
| SCHEMBL26324800 | 0.92 | TSHR (0.42) | ALDH1A1NPSR1TDP1TSHRPDCD1 | |
| SCHEMBL26324953 | 0.89 | HSD17B1 (0.40) | ALDH1A1NPSR1KMT2AHTTNPC1 | |
| SCHEMBL26324955 | 0.88 | PDCD1 (0.50) | TSHRPDCD1CD274NPC1MAPT | |
| SCHEMBL26325014 | 0.87 | PDCD1 (0.51) | TSHRPDCD1CD274NPC1MAPT | |
| SCHEMBL26324957 | 0.86 | PTGS1 (0.41) | ALDH1A1SMN1; SMN2MMP2MMP9MMP8 | |
| SCHEMBL25439798 | 0.85 | TRPM8 (0.40) | TRPM8ALDH1A1NPSR1TDP1TSHR | |
| SCHEMBL26324996 | 0.85 | ALDH1A1 (0.37) | ALDH1A1NPSR1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL26324995 | 0.84 | PTGS1 (0.42) | ALDH1A1SMN1; SMN2MMP2MMP9MMP8 | |
| SCHEMBL26324971 | 0.81 | TP53 (0.39) | TRPM8ALDH1A1NPSR1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | TRPM8 4135/4885ALDH1A1 1805/4885NPSR1 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.