Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621799 | 0.85 | MAPT (0.48) | MAPTMAPK1GAALMNATDP1 | |
| SCHEMBL24088547 | 0.85 | MAPT (0.48) | MAPTMAPK1GAALMNATDP1 | |
| SCHEMBL24088552 | 0.81 | L3MBTL1 (0.49) | MAPTMAPK1GAALMNATDP1 | |
| SCHEMBL26325839 | 0.80 | ALDH1A1 (0.44) | MAPTMAPK1GAALMNATDP1 | |
| SCHEMBL24088551 | 0.80 | L3MBTL1 (0.48) | MAPTMAPK1GAALMNATDP1 | |
| SCHEMBL24088550 | 0.80 | MAPT (0.44) | MAPTMAPK1GAAPOLBLMNA | |
| SCHEMBL24088548 | 0.78 | MAPT (0.44) | MAPTMAPK1GAALMNATDP1 | |
| Thurfyl Nicotinate SCHEMBL1065912 | 0.74 | GAA (0.50) | MAPTMAPK1GAAPOLBLMNA | |
| SCHEMBL24088549 | 0.74 | TDP1 (0.42) | MAPTMAPK1GAALMNATDP1 | |
| SCHEMBL15544733 | 0.73 | LMNA (0.54) | MAPTMAPK1GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767314-B2 | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same | CONOPCO, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767314-B2 | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same | CONOPCO, INC. (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767314-B2 | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same | PRKAG1, PRKAB1, PRKAG2 | MAPT 2136/4885MAPK1 1155/4885GAA 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.