Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20213832 | 0.83 | TAAR1 (0.46) | CYP2D6ADRB1ADRB3CYP3A4CES2 | |
| SCHEMBL10485699 | 0.83 | ADRB2 (0.65) | CYP2D6HIF1AADRB2ADRB1ADRB3 | |
| SCHEMBL26326775 | 0.82 | CYP2D6 (0.43) | CYP2D6HIF1AADRB2ADRB1KDM4E | |
| SCHEMBL26326776 | 0.81 | CYP2D6 (0.47) | CYP2D6HIF1AADRB2ADRB1KDM4E | |
| SCHEMBL26326760 | 0.78 | ADRB2 (0.43) | CYP2D6HIF1AADRB2ADRB1KDM4E | |
| SCHEMBL16371920 | 0.78 | CES2 (0.43) | ADRB2CYP3A4CES2CES1 | |
| SCHEMBL1913425 | 0.77 | CES2 (0.42) | CYP2D6CYP3A4CES2CES1MEN1 | |
| SCHEMBL4607597 | 0.75 | CNR2 (0.44) | HIF1ACYP3A4CES2CES1 | |
| SCHEMBL6630352 | 0.75 | ALDH1A1 (0.42) | CYP2D6KDM4ECYP3A4CES2CES1 | |
| SCHEMBL12312536 | 0.75 | CYP2D6 (0.54) | CYP2D6HIF1AADRB2ADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767322-B2 | Triazolopyridinyl compounds as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767322-B2 | Triazolopyridinyl compounds as kinase inhibitors | RIPK1, RIPK3, RIPK4 | CYP2D6 2658/4885HIF1A 3603/4885ADRB2 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.