SCHEMBL263464

SCHEMBL263464

CCCCCCc1cc[c]o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
PTGS2 P35354 3/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KCNH2 Q12809 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HSPD1 P10809 1/20 0.38
ADRB3 P13945 1/20 0.38
HTR2C P28335 1/20 0.38
HSPE1 P61604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422475 1.00 MAPT (0.41) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL22129744 1.00 MAPT (0.41) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL3242083 0.98 MAPT (0.39) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL10855305 0.77 SIGMAR1 (0.43) SLC6A4KCNH2KDM4EALDH1A1HTR2A
SCHEMBL8921829 0.72 EPHX2 (0.57) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL30889345 0.72 EPHX2 (0.57) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL16753020 0.72 EPHX2 (0.57) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL3924849 0.72 EPHX2 (0.57) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL10878735 0.72 EPHX2 (0.57) MAPTPTGS2ESR1ADRA2AADORA3
SCHEMBL3394938 0.69 EPHX2 (0.54) MAPTPTGS2ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902023-B1 COMPOSITION CONTAINING ORGANIC SEMICONDUCTOR, SOLUTION FOR FORMING ORGANIC SEMICONDUCTOR LAYER, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR TOSOH CORP (JP) 2024-04-24 EP disclosed
CN-115335464-B Hydrophobic coating composition 迈图高新材料公司 2024-03-26 CN disclosed
EP-4305116-A1 SILICON-BASED COMPOSITIONS AND APPLICATIONS THEREOF Momentive Performance Materials Inc. (US) 2024-01-17 EP disclosed
US-20240010786-A9 POLYOL COMPOSITIONS PRESIDIUM INNOVATIONS, LLC 2024-01-11 US disclosed
CN-113423767-B Curable silicone-based composition and use thereof 迈图高新材料公司 2024-01-09 CN disclosed
CN-117280004-A Silicon-based composition and use thereof 迈图高新材料公司 2023-12-22 CN disclosed
US-20230142592-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR TOSOH CORPORATION (JP) 2023-05-11 US disclosed
US-20230055656-A1 HYDROPHOBIC COATING COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-02-23 US disclosed
EP-4116304-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR Tosoh Corporation (JP) 2023-01-11 EP disclosed
EP-4097180-A1 HYDROPHOBIC COATING COMPOSITIONS Momentive Performance Materials Inc. (US) 2022-12-07 EP disclosed
US-20050256290-A1 Monomers and polymers comprising conjugated groups and methods for making thereof GENERAL ELECTRIC COMPANY 2005-11-17 US disclosed
WO-2005073271-A1 COMPOSITIONS USEFUL AS COATINGS, THEIR PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2005-08-11 WO disclosed
US-6924276-B2 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2005-08-02 US disclosed
US-20050159542-A1 Compositions useful as coatings, their preparation, and articles made therefrom GENERAL ELECTRIC COMPANY 2005-07-21 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
US-20040039208-A1 Process for making n-aryl-anthranilic acids and their derivatives CHEN MICHAEL HUAI GU (US) 2004-02-26 US disclosed
EP-1313694-A1 PROCESS FOR MAKING N-ARYL-ANTHRANILIC ACIDS AND THEIR DERIVATIVES WARNER-LAMBERT COMPANY (US) 2003-05-28 EP disclosed
US-20030087924-A1 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors SORENSON RODERICK JOSEPH (US) 2003-05-08 US disclosed
EP-1291345-A1 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2003-03-12 EP disclosed
WO-2002018319-A1 PROCESS FOR MAKING N-ARYL-ANTHRANILIC ACIDS AND THEIR DERIVATIVES WARNER-LAMBERT COMPANY LLC (US) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039208-A1 Process for making n-aryl-anthranilic acids and their derivatives AADAC, AHR, AADAT MAPT 4224/4885PTGS2 1561/4885ESR1 2881/4885
US-20230142592-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR CHRM1, CHRM2, ACVRL1 MAPT 2087/4885PTGS2 4058/4885ESR1 170/4885
US-20030087924-A1 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors MMP13, MMP3, MMP9 MAPT 4511/4885PTGS2 67/4885ESR1 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.