Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26374273 | 0.90 | LMNA (0.36) | ESR1LMNA | |
| SCHEMBL23418220 | 0.88 | TRPA1 (0.40) | ESR1TRPA1LMNAHSD17B10RIPK1 | |
| SCHEMBL26374261 | 0.88 | LTB4R (0.38) | ESR1LTB4RLTB4R2CTSKPRKCA | |
| SCHEMBL12578602 | 0.84 | ESR1 (0.39) | ESR1LMNACTSKMAPTOPRM1 | |
| SCHEMBL17721325 | 0.83 | RIPK1 (0.42) | TRPA1LTB4RLTB4R2RIPK1CTSK | |
| SCHEMBL2736409 | 0.82 | CYP2C9 (0.35) | ESR1LMNAHSD17B10CTSKMAPT | |
| SCHEMBL26374242 | 0.81 | ESR1 (0.32) | ESR1TRPA1LMNAHSD17B10LTB4R | |
| SCHEMBL26374254 | 0.81 | CTSK (0.32) | ESR1TRPA1LMNAHSD17B10LTB4R | |
| SCHEMBL15979584 | 0.80 | ESR1 (0.40) | ESR1LMNAHSD17B10LTB4RLTB4R2 | |
| SCHEMBL26374250 | 0.79 | ALDH1A1 (0.31) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230314943-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND METHOD FOR MANUFACTURING RESIST FILM USING THE SAME | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |