Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637483 | 0.95 | PLAT (0.43) | PLATALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2637577 | 0.74 | MAPT (0.53) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL2638131 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL2637640 | 0.72 | PDE3B (0.46) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL2637603 | 0.70 | ALOX5 (0.48) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL3411734 | 0.68 | LMNA (0.58) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL2637689 | 0.67 | CCNA2 (0.42) | PLATALDH1A1MEN1KMT2APIK3CB | |
| SCHEMBL23683888 | 0.67 | KDM4E (0.64) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL3407318 | 0.66 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL20077971 | 0.66 | LMNA (0.43) | ALDH1A1MEN1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |