Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26393692 | 0.87 | GSK3B (0.41) | LRRK2CLK4MAP3K8CDC7ABCC9 | |
| SCHEMBL26396309 | 0.87 | LRRK2 (0.45) | LRRK2CLK4MAP3K8CDC7ABCC9 | |
| SCHEMBL26394366 | 0.85 | CYP1A2 (0.59) | LRRK2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL26394054 | 0.82 | CDK7 (0.46) | LRRK2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL26393847 | 0.81 | MAP2K4 (0.41) | LRRK2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL26395345 | 0.76 | LRRK2 (0.42) | LRRK2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL26393678 | 0.75 | LRRK2 (0.41) | LRRK2CLK4MAP3K8CDC7CDK8 | |
| SCHEMBL26397024 | 0.73 | LRRK2 (0.41) | LRRK2CYP1A2CLK4MAP3K8CDC7 | |
| SCHEMBL26394712 | 0.72 | GSK3B (0.51) | CYP1A2CYP3A4CLK4CCNCCDK8 | |
| SCHEMBL11698487 | 0.70 | ITK (0.47) | LRRK2CDC7ITKABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |