Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 6/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDK8 | P49336 | 4/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.39 |
| ▸ | CLK2 | P49760 | 3/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | PAK4 | O96013 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26393847 | 0.88 | MAP2K4 (0.41) | CDK7TBK1LRRK2CLK4CDK2 | |
| SCHEMBL26394035 | 0.82 | LRRK2 (0.44) | LRRK2CLK4CDK8CDC7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL26129973 | 0.80 | ULK1 (0.46) | CDK7TBK1CLK4CDK2CDK8 | |
| SCHEMBL26394366 | 0.79 | CYP1A2 (0.59) | LRRK2CLK4CDK2CDK8DAPK3 | |
| SCHEMBL26393597 | 0.73 | DYRK1A (0.47) | CDK7CLK4CDK2CDK8DAPK3 | |
| SCHEMBL26395039 | 0.73 | HDAC6 (0.47) | CDK8JAK3JAK2CYP1A2MAPK1 | |
| SCHEMBL26395345 | 0.71 | LRRK2 (0.42) | LRRK2CLK4CDK2CDK8DAPK3 | |
| SCHEMBL26393692 | 0.70 | GSK3B (0.41) | LRRK2CLK4CDK2CDK8DAPK3 | |
| SCHEMBL26396309 | 0.70 | LRRK2 (0.45) | CDK7LRRK2CLK4CDK2CDK8 | |
| SCHEMBL2671672 | 0.70 | MAPK1 (0.50) | CDK7CDK2CDK8JAK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |