Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.46 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26393486 | 0.82 | HDAC6 (0.50) | HDAC6PAK1JAK2JAK1TYK2 | |
| SCHEMBL26394382 | 0.81 | MAP2K4 (0.59) | MAP2K4MAPK1MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL26395050 | 0.80 | AAK1 (0.55) | HDAC6GSK3BAAK1 | |
| SCHEMBL26394340 | 0.79 | GSK3B (0.47) | HDAC6MAP2K4MAPKAPK5PAK1JAK2 | |
| SCHEMBL26394420 | 0.78 | JAK2 (0.66) | HDAC6MAPK1MAPKAPK5PAK1JAK2 | |
| SCHEMBL26393770 | 0.78 | PRKAA1 (0.47) | HDAC6MAPKAPK5PAK1JAK2JAK1 | |
| SCHEMBL26396309 | 0.77 | LRRK2 (0.45) | HDAC6PAK1JAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL31243602 | 0.77 | ULK1 (0.52) | HDAC6GSK3BAAK1 | |
| SCHEMBL26393744 | 0.76 | MAP2K4 (0.46) | HDAC6MAP2K4MAPKAPK5PAK1JAK2 | |
| SCHEMBL26393597 | 0.76 | DYRK1A (0.47) | HDAC6MAPKAPK5JAK2TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |