Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.36 |
| ▸ | THRB | P10828 | 11/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23663266 | 0.83 | THRB (0.42) | THRATHRBNPBWR1ALDH1A1MCHR1 | |
| SCHEMBL26401675 | 0.82 | THRB (0.48) | THRATHRB | |
| SCHEMBL26401642 | 0.74 | THRB (0.40) | THRATHRB | |
| SCHEMBL26414144 | 0.74 | CCR5 (0.39) | THRATHRBNPBWR1ALDH1A1MCHR1 | |
| SCHEMBL23663148 | 0.73 | THRB (0.46) | THRATHRBNPBWR1ALDH1A1MCHR1 | |
| SCHEMBL23663156 | 0.71 | NPBWR1 (0.48) | THRATHRBNPBWR1ALDH1A1MCHR1 | |
| SCHEMBL23507053 | 0.70 | KDM4E (0.41) | ALDH1A1 | |
| SCHEMBL23391539 | 0.68 | CYP3A4 (0.41) | THRATHRBALDH1A1 | |
| SCHEMBL1129268 | 0.67 | ALDH1A1 (0.44) | NPBWR1ALDH1A1MCHR1POLB | |
| SCHEMBL29036495 | 0.67 | THRB (0.35) | THRATHRBNPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780825-B2 | Thyroid hormone receptor agonists and use thereof | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780825-B2 | Thyroid hormone receptor agonists and use thereof | TSHR, THRA, THRB | THRA 2/4885THRB 3/4885NPBWR1 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.