Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 6/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408251 | 0.90 | CACNA1H (0.43) | CACNA1HMGLL | |
| SCHEMBL26408263 | 0.86 | CACNA1H (0.42) | CACNA1HMGLL | |
| SCHEMBL26408705 | 0.85 | NPSR1 (0.40) | CACNA1HKDRPOLBFFAR4 | |
| SCHEMBL26408044 | 0.85 | CACNA1H (0.48) | CACNA1HMGLLFFAR4 | |
| SCHEMBL26408935 | 0.84 | CACNA1H (0.34) | CACNA1HABL1KDRBRAFPOLB | |
| SCHEMBL26464769 | 0.83 | LMNA (0.44) | POLB | |
| SCHEMBL26409305 | 0.80 | CACNA1H (0.42) | CACNA1HMGLL | |
| SCHEMBL26408941 | 0.80 | MALT1 (0.36) | CACNA1HABL1KDR | |
| SCHEMBL26465563 | 0.79 | CACNA1H (0.42) | CACNA1H | |
| SCHEMBL26408695 | 0.79 | SMN1; SMN2 (0.48) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |