SCHEMBL26415764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26415765	0.90	AKR1C3 (0.39)	AKR1C3AKR1C2ALDH1A1MAPTTNKS
	SCHEMBL26416358	0.85	ALOX5 (0.48)	AKR1C3AKR1C2ALDH1A1MAPTTNKS
	SCHEMBL9916240	0.85	ENPP3 (0.43)	AKR1C3AKR1C2ALDH1A1MAPTTNKS
	SCHEMBL9916227	0.83	TNKS (0.47)	ALDH1A1MAPTTNKSPARP1TNKS2
	SCHEMBL26415786	0.83	METAP2 (0.40)	ALDH1A1MAPTPRKDCCYP1A2ADORA1
	SCHEMBL24502102	0.82	ALOX5 (0.46)	ALDH1A1TNKSPARP1TNKS2HDAC6
	SCHEMBL9916239	0.82	TNKS (0.46)	ALDH1A1MAPTTNKSPARP1TNKS2
	SCHEMBL26496136	0.81	ALOX5 (0.43)	AKR1C3AKR1C2ALDH1A1MAPTTNKS
	SCHEMBL26415937	0.80	ALOX5 (0.46)	ALDH1A1TNKSPARP1TNKS2HDAC6
	SCHEMBL26415769	0.79	AKR1C3 (0.39)	AKR1C3AKR1C2UGT2B7CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.