SCHEMBL26426445

SCHEMBL26426445

CCC(C)c1cc(-c2cccc3c2oc2c(-c4ccccc4)cccc23)c2ccccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.38
JAK1 P23458 1/20 0.38
TYK2 P29597 1/20 0.38
PPARG P37231 3/20 0.36
PPARA Q07869 3/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
MPI P34949 1/20 0.35
ADORA3 P0DMS8 2/20 0.34
ADORA2A P29274 2/20 0.34
ADORA1 P30542 2/20 0.34
PRKDC P78527 4/20 0.34
ALOX5 P09917 1/20 0.34
PIK3CD O00329 3/20 0.33
PIK3CA P42336 3/20 0.33
PIK3CB P42338 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26415786 0.87 METAP2 (0.40) JAK2JAK1TYK2PPARGPPARA
SCHEMBL26415765 0.81 AKR1C3 (0.39) JAK2JAK1TYK2PPARGPPARA
SCHEMBL26418833 0.76 ALDH1A1 (0.40) JAK2JAK1TYK2KDM4EALDH1A1
SCHEMBL23197839 0.75 MAOB (0.42) JAK2JAK1TYK2KDM4EALDH1A1
SCHEMBL26415764 0.73 AKR1C3 (0.39) PPARGPPARAKDM4EALDH1A1MAPT
SCHEMBL26415716 0.73 ALOX5 (0.49) KDM4EALDH1A1MAPTHPGDPRKDC
SCHEMBL4549422 0.72 ALOX5 (0.45) JAK2JAK1TYK2PRKDCALOX5
SCHEMBL9917186 0.72 ALOX5 (0.50) PRKDCALOX5PIK3CDPIK3CBCYP2C9
SCHEMBL430105 0.72 PRKDC (0.46) KDM4EALDH1A1HPGDPRKDCALOX5
SCHEMBL11713826 0.72 PRKDC (0.47) KDM4EALDH1A1HPGDPRKDCALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME MAOA, MAOB, AOC2 JAK2 1945/4885JAK1 1277/4885TYK2 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.