SCHEMBL26428548

SCHEMBL26428548

NC(=O)[C@@H]1CCCN1C(=O)CCc1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.52
HTR1A P08908 8/20 0.47
HTR7 P34969 8/20 0.47
PREP P48147 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ACE P12821 1/20 0.46
UTS2R Q9UKP6 1/20 0.45
F2 P00734 1/20 0.45
NTMT1 Q9BV86 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26425956 0.96 DPP4 (0.48) DPP4HTR1AHTR7PREPMEN1
SCHEMBL26418988 0.85 PREP (0.45) DPP4PREPMEN1KMT2AUTS2R
SCHEMBL26421741 0.81 MAPK1 (0.61) DPP4MEN1KMT2A
SCHEMBL5737566 0.80 P2RX7 (0.55) DPP4PREPMEN1KMT2AF2
SCHEMBL26429036 0.78 GRM2 (0.43) PREP
SCHEMBL26425916 0.77 MTNR1A (0.41) PREPMEN1KMT2A
SCHEMBL26425154 0.77 MPO (0.60) DPP4HTR1AHTR7KMT2A
SCHEMBL5546470 0.77 ACE (0.57) ACEF2
SCHEMBL25994667 0.77 UTS2R (0.61) DPP4PREPMEN1KMT2AACE
SCHEMBL7284471 0.76 DPP4 (0.47) DPP4PREPMEN1KMT2AUTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed