Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26094254 | 0.78 | KDM4E (0.57) | NPSR1 | |
| SCHEMBL1189319 | 0.75 | NPSR1 (0.51) | OPRM1OPRK1OPRL1OPRD1NPSR1 | |
| SCHEMBL13597028 | 0.74 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL29304439 | 0.73 | L3MBTL3 (0.51) | OPRM1OPRK1OPRL1OPRD1CYP2D6 | |
| SCHEMBL26094127 | 0.72 | MEN1 (0.62) | OPRM1OPRD1NPSR1GPR55CYP3A4 | |
| SCHEMBL1189507 | 0.72 | ALDH1A1 (0.49) | OPRM1OPRK1OPRL1OPRD1NPSR1 | |
| SCHEMBL16449042 | 0.70 | L3MBTL3 (0.51) | OPRM1OPRK1OPRL1OPRD1CYP3A4 | |
| SCHEMBL28263429 | 0.68 | HRH3 (0.48) | DPP4HTR2AHTR2CHTR2BL3MBTL3 | |
| SCHEMBL17049270 | 0.68 | OPRM1 (0.56) | OPRM1OPRK1OPRL1OPRD1NPSR1 | |
| SCHEMBL13597004 | 0.68 | L3MBTL1 (0.56) | OPRM1OPRK1OPRL1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |