Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771595 | 0.89 | ALDH1A1 (0.60) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL954217 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL20536005 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL5872583 | 0.79 | ALDH1A1 (0.72) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL8066632 | 0.77 | ALDH1A1 (0.75) | ALDH1A1TSHRMAPK1CYP3A4GRIN2D | |
| SCHEMBL1116034 | 0.76 | CYP3A4 (0.58) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL11745815 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL9771768 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL6673368 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TSHRMAPTTP53LMNA | |
| SCHEMBL8874607 | 0.75 | TSHR (0.59) | ALDH1A1TSHRMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112374996-A | Preparation method of 3, 5-dichloro o-phenylenediamine | 宁夏大学 | 2021-02-19 | — | — | CN | claimed |
| CN-112374996-A | Preparation method of 3, 5-dichloro o-phenylenediamine | 宁夏大学 | 2021-02-19 | — | — | CN | disclosed |
| EP-2848613-B1 | DIAMINOARYL DERIVATIVES SUBSTITUTED BY CARBAMATE AND PESTICIDAL COMPOSITION CONTAINING SAME | KYUNG NONG CORP (KR) | 2016-09-21 | — | — | EP | disclosed |
| US-9018233-B2 | Diaminoaryl derivatives substituted by carbamate and pesticidal composition containing same | KYUNG NONG CORPORATION (KR) | 2015-04-28 | — | — | US | disclosed |
| US-9018233-B2 | Diaminoaryl derivatives substituted by carbamate and pesticidal composition containing same | KYUNG NONG CORPORATION (KR) | 2015-04-28 | — | — | US | disclosed |
| US-9018233-B2 | Diaminoaryl derivatives substituted by carbamate and pesticidal composition containing same | KYUNG NONG CORPORATION (KR) | 2015-04-28 | — | — | US | disclosed |
| US-20150094342-A1 | DIAMINOARYL DERIVATIVES SUBSTITUTED BY CARBAMATE AND PESTICIDAL COMPOSITION CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2015-04-02 | — | — | US | disclosed |
| US-20150094342-A1 | DIAMINOARYL DERIVATIVES SUBSTITUTED BY CARBAMATE AND PESTICIDAL COMPOSITION CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2015-04-02 | — | — | US | disclosed |
| US-20150094342-A1 | DIAMINOARYL DERIVATIVES SUBSTITUTED BY CARBAMATE AND PESTICIDAL COMPOSITION CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2015-04-02 | — | — | US | disclosed |
| EP-2848613-A1 | DIAMINOARYL DERIVATIVES SUBSTITUTED BY CARBAMATE AND PESTICIDAL COMPOSITION CONTAINING SAME | Kyung Nong Corporation (KR) | 2015-03-18 | — | — | EP | disclosed |
| US-7728025-B2 | 2-heteroaryl-substituted benzimidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| WO-2008124665-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | disclosed |
| US-4863482-A | FROM A TRIHALONITROBENZENE | L'OREAL (FR) | 1989-09-05 | — | — | US | disclosed |
| EP-0303826-A1 | Substituted 2-nitro metaphenylene diamines, process for their preparation and their use in dyeing keratinous fibres and especially human hair | L'OREAL (FR) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094342-A1 | DIAMINOARYL DERIVATIVES SUBSTITUTED BY CARBAMATE AND PESTICIDAL COMPOSITION CONTAINING SAME | DDT, DDC, DPP3 | ALDH1A1 2870/4885TSHR 3134/4885MAPT 2876/4885 |
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | NR3C1, MC2R, NR3C2 | ALDH1A1 4345/4885TSHR 182/4885MAPT 242/4885 |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | GCK, GCKR, HK1 | ALDH1A1 1188/4885TSHR 3405/4885MAPT 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.