Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466216 | 0.87 | CACNA1H (0.47) | CACNA1HALDH1A1DRD4POLBACKR3 | |
| SCHEMBL26464502 | 0.87 | CACNA1H (0.50) | CACNA1HALDH1A1SMN1; SMN2DRD4MAPT | |
| SCHEMBL26464500 | 0.85 | CACNA1H (0.70) | CACNA1HDRD4MAPTHTT | |
| SCHEMBL26465812 | 0.84 | CACNA1H (0.47) | CACNA1HALDH1A1LMNAPOLBMAPT | |
| SCHEMBL26465562 | 0.83 | SMN1; SMN2 (0.57) | CACNA1HALDH1A1SMN1; SMN2DRD4POLB | |
| SCHEMBL26465699 | 0.81 | HPGD (0.55) | CACNA1HALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL26465696 | 0.79 | CACNA1H (0.44) | CACNA1HALDH1A1DRD4 | |
| SCHEMBL26465810 | 0.78 | CACNA1H (0.47) | CACNA1HALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL26465838 | 0.78 | CACNA1H (0.55) | CACNA1HALDH1A1DRD4 | |
| SCHEMBL26465708 | 0.78 | CACNA1H (0.49) | CACNA1HALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |