Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26464503 | 0.87 | KCNT1 (0.49) | ALDH1A1CACNA1HKMT2ALMNAPOLB | |
| SCHEMBL26465708 | 0.83 | CACNA1H (0.49) | ALDH1A1CACNA1HKMT2AMAPTTSHR | |
| SCHEMBL26465562 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1CACNA1HKMT2AMAPTTSHR | |
| SCHEMBL26465573 | 0.82 | CACNA1H (0.72) | ALDH1A1CACNA1HKMT2ALMNASMN1; SMN2 | |
| SCHEMBL26465833 | 0.80 | CACNA1H (0.56) | ALDH1A1CACNA1HKMT2ALMNASMN1; SMN2 | |
| SCHEMBL26465699 | 0.78 | HPGD (0.55) | ALDH1A1CACNA1HKMT2AMAPTTSHR | |
| SCHEMBL26465812 | 0.78 | CACNA1H (0.47) | ALDH1A1CACNA1HKMT2AMAPTTSHR | |
| SCHEMBL26465810 | 0.78 | CACNA1H (0.47) | ALDH1A1CACNA1HMAPTUSP2LMNA | |
| SCHEMBL26465710 | 0.77 | HTT (0.50) | ALDH1A1CACNA1HKMT2ATSHRLMNA | |
| SCHEMBL26465838 | 0.75 | CACNA1H (0.55) | ALDH1A1CACNA1HRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |